The ointment base is that substance or part of an ointment preparation which serves as carrier or vehicle for the medicament. Home medical reference and training manuals watersoluble bases compounding and manufacturing. Classification of ointment bases compounding and manufacturing. In some instances it is necessary to use an ointment base that is less than ideal. Take about 5 g of each ointment and note the appearance.
Medisca offers compound pharmacies over 600 equipment and devices that meet or exceed the needs of todays pharmaceutical compounding industry. Students used the flowchart throughout the semester in both dry and wet laboratory activities. Hydrocarbon bases hydrocarbon bases, known also as oleaginous ointment bases, are represented by white petrolatum and white ointment both usp. Experimental studies on the penetration of the following substances. Spectrum specializes in providing the top ointment base excipients but if you do not see the product, grade or form of the ingredient you require, just contact our chemical specialist at 8007728786. In some cases, it is necessary to use a base that is less than ideal in order to achieve the stability required. Each ointment base type has different physical characteristics and therapeutic uses based upon the nature of its components. Under the proposed nomenclature, this situation would be. Once congealed, the ointment may be passed through an ointment mill in largescale manufacture or rubbed with a spatula or in a mortar to ensure a uniform texture. Paraffin ointment consists of a mixture of bees wax, hard paraffin, and soft paraffin. Ointment bases are prepared by mixing up to 50% emulsifying wax with liquid or soft paraffi ns. Ointments and pastes are among the dosage forms used. Introduction herbal drugs are formulated in the form of ointment and are used topically for several purposes, e.
Ointmentointment ointment basesointment bases preparation of thepreparation of the ointmentsointments storage andstorage and dispensingdispensing 9. It is watersoluble, waterwashable, and can absorb water. At the end of the semester, students completed a dry laboratory practical that required them to select an appropriate ointment base and levigating agent. Presentations ppt, key, pdf logging in or signing up. The medicated stuff or the ingredients present inside the ointment is actually the main base of ointments.
Each therapeutic ointment possesses as its base a representative of one of these four general classes. Zopf, college of pharmacy, state university of iowa college of pharmacy, state university of iowa. Effect of plant extracts formulated in different ointment. Capacity of various ointment bases to absorb solvents. Base the lowest and most visible part of a building, often treated with distinctive materials, such as rustication. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Information and translations of ointment bases in the most comprehensive dictionary definitions resource on the web. In addition to the soft paraffins two other ointment bases of this type have been carried over from the b. Ointment definition of ointment by medical dictionary. These bases were selected for formulation of the plant extract in the form of an ointment. In the chemical processes of the body, bases are essential to the maintenance of a normal acidbase balance.
Ointment base article about ointment base by the free. Topical base a traditional oilinwater emulsion containing petrolatum and propylene glycol. Ointment information, ointment bases, ointment types, list. Midicinal application of the ointment what is ointments. The ointments showed bactericidal activity within 2 h against resistant strain of pseudomonas spp. Middle english oinement, from old french oignement, from vulgar latin unguimentum, from latin unguentum.
Ointment bases the pharmaceutics and compounding laboratory. Ointment bases recognized for use as vehicles fall into four general classes. It seems there is much foopah by the organicgreen sector of society towards petroleum jelly vaseline when used as an ointment base, but knowing more about petroleum jelly and why it is still one of the most highly used and effective ointment bases is something the greater majority simply do not want to know as they believe vaseline is linked to the evil oil. Choice of base the choice of an ointment base depends upon many factors, such as the action desired, the nature of the medicament to be incorporated and its bioavailability and stability, and the requisite shelflife of the finished product. Based on their makeup, ointment bases have varying capacities to absorb liquids. Ointment bases are generally classified by the usp into four groups. Data sources include ibm watson micromedex updated 4 may 2020, cerner multum updated 4 may 2020. Petro waxes in ointment bases article in journal of the american pharmaceutical association 324. The following table summarizes the composition, properties, and common uses of each of the five types. If you have a question about a specific product or placing your order, our team can help. Ointment definition of ointment by the free dictionary. An ointment base useful for preparing topically applied medicament formulations, comprising a stable emulsion of at least about 10% by weight of each of water, one or more paraffins, and a liquid polyol. Procure vitamin a and d skin protectant ointment twin. Set aside at least 55 g to use next week in step 4 below.
A highly viscous or semisolid substance used on the skin as a cosmetic, emollient, or medicament. This yields an ointment of stiffer consistence and is the base used for ointment of boric acid. Each therapeutic ointment possesses as its base one of these four general classes. Ointment base useful for pharmaceutical preparations. An antiseptic ointment is used to destroy or inhibit the growth of bacteria. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
Medisca provides compounding pharmacies with diverse line of quality assured bases such as gels, creams, ointments and oral vehicles. An ideal ointment base should be inert, stable, smooth, compatible with the skin, nonirritating and should release the incorporated medicaments readily. The ointment is applied as a narrow band of approximately 0. Official ointments consist of medicinal substances incorporated in suitable vehicles bases. Ointment base definition of ointment base by the free. Although emulsifying wax is compatible with many acids and alkalis, it is incompatible with many cationic materials and polyvalent metal salts. The superiority of the emulsifying bases is rather well known and both the water inoil and the oilinwater emulsions have established their places in. Lubricant pm mineral oil, white petrolatum ointment. Most oils mix easily with hydrocarbon bases, but they reduce the viscosity of the preparation. Toxicity test carried out on sprague dawley rats showed no erythema, edema and. Only small amounts of an aqueous component can be incorporated into these bases. Extemporaneous compounding of medicated ointment ijpc. Ointment bases, may by used for their physical effects or as vehicles for medicated ointments. All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice.
Properties of ointment bases vary greatly, and active ingredients are frequently. A flowchart was designed to help students select the appropriate base for an ointment. In light of the high drug content, this point is particularly important in the formulation of pastes. Topical base an anhydrous, nonocclusive, lipidfree ointment base. Concomitant use of salicylic acid ointment bp and other topical medicines on the same area of skin should therefore be avoided. Gel bases ointments compounding bases pharmaceuticals. Ointment bases, australasian journal of dermatology 10. There are five 5 classes or types of ointment bases which are differentiated on the basis of their physical composition. Home medical reference and training manuals absorption bases. Types of ointment bases hydrocarbon bases absorption bases nonemulsified bases water. Medisca provides compounding pharmacies with diverse line of qualityassured bases such as gels, creams, ointments and oral vehicles. Nevertheless, also because of its water content, preservatives have to. Pharmacology a fatty or oily medicated formulation applied to the. The bases used are combinations of peg 300 and peg 3350, cetyl alcohol and cetyl esters, wax, liquid paraffin and white paraffin.
Find patient medical information for ointment base no. Types of ointment bases type of base ointement is the purine base always binds to a pyrimidine base download here free healthcaremagic app to ask a doctor. Rectal ointments these are the ointments to be applied to the peri anal or within the anal canal. Ointments and creams are the semisolid dosage forms and intended for topical application to the skin, placed on the surface of eye, or used nasally, vaginally or rectally for therapeutic or protective action or cosmetic function. A comparative study of the use of hydrophilic absorption ointment. Download our product enquiry here as a pdf or word document. Ointment bases are always anhydrous and generally contain one or more. Describe the appearance and consistency texture of each ointment base.
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